News

UCSF Magazine

The Quest to Reinvent Anesthesia

Department of Pharmaceutical Chemistry Professors Brian Shoichet, PhD ’91, and Jason Sello, PhD, are leading a collaborative research project to scour millions of compounds — with help from tiny zebrafish — to create anesthetics safe enough to use without an anesthesiologist.

Suzan Revah

Wells Lab Shows How Oxygen Deprivation Rewires Pancreatic Tumors

Recently published findings reveal how the hypoxic, or low-oxygen, environment characteristic of pancreatic cancer reshapes the proteolytic landscape of the tumor, a discovery that could translate into better diagnostic tools or treatments.

Suzan Revah

James Fraser Honored with Carl Brändén Award from The Protein Society

The Department of Bioengineering and Therapeutic Sciences chair was honored for pioneering advances in room-temperature X-ray data collection techniques and ensemble modeling methods, which have enabled deeper understanding and engineering of proteins. He has also been a champion of collaborative, project-based learning and has advocated for greater accessibility in scientific publishing. 

Suzan Revah

The Science of Smell: Q&A with Aashish Manglik, MD, PhD

We asked the Department of Pharmaceutical Chemistry associate professor how helping to uncover the fundamental principles of our smell perception could improve understanding of how other proteins in the body recognize small molecules, including potential new drugs.

Suzan Revah

$25 Million Federal Defense Grant Funds Anesthesia Innovation

Department of Pharmaceutical Chemistry faculty members Brian Shoichet, PhD, and Jason Sello, PhD, combine collaboration, curiosity, and innovation to discover molecules that can become anesthetics administered without specialized training.

Suzan Revah

A new vision for the Small Molecule Discovery Center

Charles Hart, PhD, director of the Catalyst Program, joins Department of Pharmaceutical Chemistry Chair Michelle Arkin in the center’s ongoing collaboration with academics, government labs, and pharmaceutical companies to develop drug leads that address unmet medical needs.