- About
- Research
- Research Overview
- Chemical Biology and Medicinal Chemistry
- Chemical Biology and Medicinal Chemistry Overview
- Discovering Enzyme Substrates and Functions
- Discovering Protein Ligands to Probe and Alter Function
- Discovering Enzyme Activators
- Analyzing Mechanisms of Drug Resistance via Chemical Biology
- Analyzing Enzyme Conformational Dynamics, Substrate Binding, and Catalysis
- Effective Drug Targeting of Pathogens via Medicinal Chemistry
- Computational Chemistry and Biology
- Computational Chemistry and Biology Overview
- Modeling protein regulation via allostery and post-translational modifications
- Visualizing and integrating bioinformatics and biomolecular data
- Modeling membrane permeation to optimize pharmacokinetics
- Determining enzyme function by predicting substrate specificity
- Physical Biology
- Protein and Cellular Engineering
- Protein and Cellular Engineering Overview
- Monitoring enzyme activity and disease biomarkers
- Generating human proteome antibodies via phage display and directed evolution
- Globally analyzing and dissecting apoptosis
- Proximity tagging of protein-protein interactions
- Investigating cellular interactions in tissues
- Creating fluorescent probes targeting the genome and key bio-pathways
- De novo design of catalytic and membrane proteins
- Probing and modulating membrane proteins
- Education
- People
- News
- Events
News

An illustration of neurons along with two types of damaging protein aggregates found in the Alzheimer’s disease brain: beta-amyloid plaques (brown) and tau protein tangles (blue). UCSF researchers have discovered a third type of aggregate associated with the disease, made of fragments of tau protein (not depicted).
Credit: NIH
Tue Jun 21, 2022
Pharmaceutical chemist Arkin and neurologist Grinberg discover a new protein aggregate in Alzheimer’s disease.
Thu Dec 9, 2021
Scientists at the UCSF Quantitative Biosciences institute developed a new approach for understanding cancer and applied it to breast cancer and cancers of the neck and head
Thu Nov 18, 2021
The dean’s final update, including a major advance in tuberculosis treatment and leading UCSF on energy-efficient freezers.
Wed Nov 10, 2021
The UCSF School of Pharmacy and Supply Chain Management work to halve the carbon footprint of ultra-low temperature storage
Mon Nov 8, 2021
PharmD students organized the annual Vaccinate the Dean event and administered the influenza vaccine to Dean Joseph Guglielmo, PharmD.
Wed Jul 14, 2021
School leadership changes, our ongoing fight against COVID-19, and the latest accomplishments of students, faculty members, and staff members
Wed Jun 30, 2021
Research into SARS-CoV-2 variants and potential therapies pushes forward
Thu Jun 17, 2021
The School is now recycling much of the helium used in its NMR facilities.
Thu Apr 29, 2021
Faculty members have until May 14 to apply for “risky and innovative research” funding from the Chan Zuckerberg Biohub.
Wed Apr 28, 2021
The Wells Lab developed an efficient test for SARS-CoV-2 antibodies