- About
- Research
- Research Overview
- Chemical Biology and Medicinal Chemistry
- Chemical Biology and Medicinal Chemistry Overview
- Discovering Enzyme Substrates and Functions
- Discovering Protein Ligands to Probe and Alter Function
- Discovering Enzyme Activators
- Analyzing Mechanisms of Drug Resistance via Chemical Biology
- Analyzing Enzyme Conformational Dynamics, Substrate Binding, and Catalysis
- Effective Drug Targeting of Pathogens via Medicinal Chemistry
- Computational Chemistry and Biology
- Computational Chemistry and Biology Overview
- Modeling protein regulation via allostery and post-translational modifications
- Visualizing and integrating bioinformatics and biomolecular data
- Modeling membrane permeation to optimize pharmacokinetics
- Determining enzyme function by predicting substrate specificity
- Physical Biology
- Protein and Cellular Engineering
- Protein and Cellular Engineering Overview
- Monitoring enzyme activity and disease biomarkers
- Generating human proteome antibodies via phage display and directed evolution
- Globally analyzing and dissecting apoptosis
- Proximity tagging of protein-protein interactions
- Investigating cellular interactions in tissues
- Creating fluorescent probes targeting the genome and key bio-pathways
- De novo design of catalytic and membrane proteins
- Probing and modulating membrane proteins
- Education
- People
- News
- Events
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We explore fundamental biological mechanisms and molecules of therapeutic relevance for better health, empowered by novel technologies at the interface of chemistry, physics, and computational sciences.
Recent news
Tue Jan 31
Media coverage
Thu Mar 11
Research areas
Research services and facilities
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Access small molecules as chemical tools and for drug discovery.
Small Molecule Discovery CenterLearn more -
Explore tools to characterize and interpret genomic data.
Sequence Analysis and Consulting ServiceLearn more -
Request mass spectrometry sample analysis.
National Bio-Organic Biomedical Mass Spectrometry Resource CenterLearn more -
Request state-of-the-art NMR spectroscopy for research.
Nuclear Magnetic Resonance LaboratoryLearn more -
Request renewable antibodies for human transcription factors and membrane proteins.
Antibiome CenterLearn more -
Access software tools for molecular visualization and analysis.
Resource for Biocomputing, Visualization, and InformaticsLearn more
