- About
- Research
- Research Overview
- Chemical Biology and Medicinal Chemistry
- Chemical Biology and Medicinal Chemistry Overview
- Discovering Enzyme Substrates and Functions
- Discovering Protein Ligands to Probe and Alter Function
- Discovering Enzyme Activators
- Analyzing Mechanisms of Drug Resistance via Chemical Biology
- Analyzing Enzyme Conformational Dynamics, Substrate Binding, and Catalysis
- Effective Drug Targeting of Pathogens via Medicinal Chemistry
- Computational Chemistry and Biology
- Computational Chemistry and Biology Overview
- Modeling protein regulation via allostery and post-translational modifications
- Visualizing and integrating bioinformatics and biomolecular data
- Modeling membrane permeation to optimize pharmacokinetics
- Determining enzyme function by predicting substrate specificity
- Physical Biology
- Protein and Cellular Engineering
- Protein and Cellular Engineering Overview
- Monitoring enzyme activity and disease biomarkers
- Generating human proteome antibodies via phage display and directed evolution
- Globally analyzing and dissecting apoptosis
- Proximity tagging of protein-protein interactions
- Investigating cellular interactions in tissues
- Creating fluorescent probes targeting the genome and key bio-pathways
- De novo design of catalytic and membrane proteins
- Probing and modulating membrane proteins
- Education
- People
- News
- Events
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We explore fundamental biological mechanisms and molecules of therapeutic relevance for better health, empowered by novel technologies at the interface of chemistry, physics, and computational sciences.
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Research areas
Research services and facilities
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Request mass spectrometry sample analysis.
National Bio-Organic Biomedical Mass Spectrometry Resource Center
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Request state-of-the-art NMR spectroscopy for research.
Nuclear Magnetic Resonance Laboratory
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Request renewable antibodies for human transcription factors and membrane proteins.
Antibiome Center
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Access small molecules as chemical tools and for drug discovery.
Small Molecule Discovery Center
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Access software tools for molecular visualization and analysis.
Resource for Biocomputing, Visualization, and Informatics
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Explore tools to characterize and interpret genomic data.
Sequence Analysis and Consulting Service
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