Categories: Research

James A. Wells, PhD, an internationally recognized biochemist and leader in the development of new technologies for engineering proteins and for identifying small molecules to aid drug discovery, has been named chair of the Department of Pharmaceutical Chemistry in the UCSF School of Pharmacy. His...

Brian Shoichet, PhD, School of Pharmacy faculty member and Brian Feng, PhD, former staff research associate with the School, and colleagues have discovered that many amyloid inhibitors, which scientists had hoped would keep "sticky" amyloid protein fibers such as those associated with Alzheimer's...

School of Pharmacy faculty member and computational biologist Andrej Sali, PhD, and international colleagues have developed new techniques to reveal the architecture of large protein complexes within cells. Their ultimate goal is to see how these complexes interact in real time—however fleeting the...

A research paper authored by UCSF School of Pharmacy faculty member Brian Shoichet, PhD, and colleagues appeared in the September 2007 list of The Nature Top Ten. The listing includes articles most frequently downloaded from the Nature website the preceding month.

The evaluation of large amounts of biological information can help infer the function of many enzymes in the body, but for some enzymes that are not related to proteins whose activity is already understood, bioinformatics can be unreliable.

Christopher A. Voigt, PhD, faculty member in the UCSF School of Pharmacy, is studying how to engineer living systems to solve widespread problems of society, such as our dependence on petroleum-based fuels.

Mass spectrometry technology and techniques are key to knowing the structure and function of proteins and how they act in the constantly moving highways of biological systems. Alma Burlingame, PhD, faculty member in the UCSF School of Pharmacy's department of pharmaceutical chemistry is a master of...

By understanding the complicated systems that make up biology, we will understand more about the individual parts, how they work together, communicate, and mobilize into action, according to Chao Tang, PhD, UCSF School of Pharmacy faculty member.

UCSF School of Pharmacy faculty member James Wells, PhD, director of the Small Molecule Discovery Center, describes his approach, which uses precise, sophisticated matchmaking techniques, to improving the success rate of finding chemical compounds with the potential to become drugs.

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Science could benefit from funding for deep innovation and time to dream, says Ken Dill, PhD, UCSF School of Pharmacy faculty member and associate dean of research.

Learn more about Dill's perspective in a two-part interview in Science Café, a UCSF weekly highlighting the culture, conduct, and...