Categories: Research

A technology developed in the laboratory of James Wells, PhD, chair of the Department of Pharmaceutical Chemistry, UCSF School of Pharmacy, will drive a new approach to cancer treatment that switches on or triggers, with small molecules, the enzymes called caspases that promote cell death.

Research results published from the UCSF research laboratory of Danica Galonić Fujimori, PhD, have revealed a radical approach employed by bacteria to alter their ribosomes and thereby evade antibiotics. These findings could ultimately lead to the development of ways to block this enzymatic...

James Wells, PhD, chair of the UCSF School of Pharmacy's Department of Pharmaceutical Chemistry, has been named the 2010 recipient of the American Society for Biochemistry and Molecular Biology (ASBMB) Merck Award for his pioneering studies in the field of protein engineering.

Ken Dill, PhD, an internationally recognized expert on protein folding and UCSF School of Pharmacy associate dean of research, has been named recipient of the 53rd UCSF Academic Senate Research Lectureship for his distinguished contributions to science.

UCSF's Small Molecule Discovery Center (SMDC) announced on February 18, 2010 that it has signed its first major industry partnership agreement since the SMDC was founded in 2005. The agreement is with Genentech, Inc. to discover and develop drug candidates for neurodegenerative diseases.

Wired Science has cited a computational model developed in the UCSF School of Pharmacy under the direction of faculty member Brian Shoichet, PhD, and applied and tested by scientists at the University of North Carolina at Chapel Hill School of Medicine, as one of the Top Scientific Breakthroughs...

Research directed by senior author James Wells, PhD, chair of the Department of Pharmaceutical Chemistry, UCSF School of Pharmacy, has opened the door to a new way of studying and better understanding the processes of cell death (apoptosis), blood clotting, and other biochemical pathways.

A computational method developed in the UCSF School of Pharmacy under the direction of faculty member Brian Shoichet, PhD, has the potential to predict new target diseases for existing drugs as well as unexpected side effects of approved drugs.

The Scientist has cited a UCSF innovation among its top 10 list of tools to hit the life sciences in 2009. In the spotlight is a paper that reveals how to import plant "light switches" into mammalian cells to control complex regulatory processes. The paper appeared in the October 15, 2009 issue of...