News
Fri Jan 31, 2025
A new therapy combines a drug to mark cancer cells for destruction and a radioactive antibody to kill them, while calculating an extremely safe dose of radiation that uses only the amount of radiation needed to beat the cancer.
Wed Jun 8, 2016
Pharmaceutical Chemistry department members have received the following grants and fellowships between April and June 2016:
6/9/2016: The National Science Foundation awarded Steven Altschuler a grant for his project entitled "Collaborative Research: The Genetic, Epigenetic, and Immunological Foundation of Cancer Evolution.” This project...
Wed Jun 1, 2016
Education: Evolving PharmD curriculum, Daniels Curriculum Awards; Collaborations and partnerships: pharmacy residency, UCSF/Haas MD/PhD startup marketplace; Patient care: SB 493 update; Faculty honors: Benet, Abate, Craik, Wells, Kroon, Corelli, Hudmon, Bourdet, Fischbach; Research publications: genetic testing, pharmacogenomics, cancer,...
Thu May 5, 2016
Predicting difficult-to-detect drug binding sites
Most drugs are comprised of small molecules that pass through cell membranes and are designed to bind to much larger protein molecules at exposed concave pockets. But in many disease-associated proteins, these binding sites are difficult to detect. Concave pockets may form only in the immediate...
Tue May 3, 2016
John Gross, PhD, Department of Pharmaceutical Chemistry, has been promoted to full professor.
Researchers in the Gross Lab combine a wide variety of molecular biology and quantitative biochemistry techniques with biophysics and structural biology experiments, such as NMR spectroscopy and X-ray crystallography, in order to understand how...
Fri Apr 29, 2016
Computer models provide optimal dosing for pediatric TB meningitis
Tuberculous meningitis (TBM) is an inflammation of membranes lining the brain and spine (central nervous system, CNS) due to infection with TB bacteria. TBM is especially devastating in young children, in whom it is most common, carrying a high risk of death or severe...
Thu Apr 28, 2016
In a major breakthrough, scientists at the Gladstone Institutes, led by UCSF School of Pharmacy faculty member Sheng Ding, PhD, have transformed skin cells into heart and brain cells using combinations of chemicals.
All previous work on cellular reprogramming required adding external genes to the cells, making this accomplishment an...
Fri Apr 15, 2016
Pharmaceutical Chemistry faculty members have published the following manuscripts between January and March 2016:
saRNA-guided Ago2 targets the RITA complex to promoters to stimulate transcription. Portnoy V, Lin SH, Li KH, Burlingame A, Hu ZH, Li H, Li LC. Cell Res. 2016 Mar;26(3):320-35.
Quantitative MS-...
Mon Apr 11, 2016
Members of the Department of Pharmaceutical Chemistry have received the following grants and fellowships between January and March 2016:
Date
Item
3/3/2016
Zachary Hill, a postdoc in the Wells Lab, received a prestigious...