Categories: Research

How do you discover new drugs against diseases such as cancer?

Cataracts are the leading cause of blindness worldwide, the leading cause of vision loss in the United States, and cases are increasing with an aging population. Currently the condition can be treated with surgery—an expensive intervention that leaves most patients blinded in developing countries...

More than a quarter of all drugs work by targeting one of a large family of proteins called G-protein-coupled receptors (GPCRs). Hundreds of different GPCRs are embedded in cell membranes, converting stimuli from the outside world—neurotransmitters, hormones, even light—into intracellular signals...

The next frontier in developing therapies for cancer and other diseases could come through studying organ development or tumor growth in living humans. Problem is, there’s no ethical way of doing that using current technology.

Zev Gartner, PhD, has focused on the next best thing: His lab is...

Sheng Ding, PhD, is a stem cell scientist who uses novel small molecules to control and reprogram stem cell activities in various tissue types. Applying his groundbreaking techniques, he has previously succeeded in transforming skin cells into functional brain, heart, liver, and insulin-producing...

A new collaboration between Celgene Corp. and the Recombinant Antibody Network (RAN) will support the development of next-generation, antibody-based cancer therapies. The RAN is a consortium comprising researchers from the UCSF School of Pharmacy (UCSF Antibiome Center), the University of Chicago,...