Topics and Expertise: drug discovery and development

UCSF-led collaboration uncovers new avenues for COVID-19 drug discovery

The QBI Coronavirus Research Group found six drugs that effectively beat back SARS-COV-2 in the laboratory.

The UCSF School of Pharmacy is moving quickly against the COVID-19 pandemic, applying a scientific mindset to challenges being raised during the crisis.

Michelle Arkin, PhD, has received the 2018 Breakthrough Science Initiative Award from the Ono Pharma Foundation to study a class of proteins, called 14-3-3 proteins, known to be involved in various cancers, with the ultimate goal of enabling discoveries that lead to new ways to treat cancer.

A pioneering public/private consortium is poised to turn the marathon of drug discovery into a team relay, maybe even a short one.

For decades, scientists have wanted to be able to study dopamine receptors one by one. The brain’s dopamine receptors are responsible for a variety of behaviors, such as reward seeking, and are also involved in psychiatric illnesses like schizophrenia.

Renowned researcher and educator Matthew Jacobson, PhD, has been named the new chair of the UCSF School of Pharmacy’s Department of Pharmaceutical Chemistry. His appointment by Dean B. Joseph Guglielmo, PharmD, will be effective January 15, 2016.

New computer models were able to successfully predict negative side effects for hundreds of currently marketed drugs, report researchers from the UCSF School of Pharmacy, SeaChange Pharmaceuticals, and Novartis Institutes for Biomedical Research in a paper published online this week in the journal...

James Wells, PhD, chair, department of pharmaceutical chemistry in the UCSF School of Pharmacy, shares his thoughts on the need for increased public awareness about the ultimate value of science to health and the opportunities now presenting themselves to university scientists to become more...

Through study results of a particular enzyme of unknown function, called Tm0936, that is found in a bacterium that lives in thermal vents in the Mediterranean Ocean, UCSF School of Pharmacy faculty member Brian Shoichet, PhD and colleagues are shedding light on how to ultimately better predict the...