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Department of Pharmaceutical Chemistry
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  • Research
    • Research Overview
    • Chemical Biology and Medicinal Chemistry
      • Chemical Biology and Medicinal Chemistry Overview
      • Discovering Enzyme Substrates and Functions
      • Discovering Protein Ligands to Probe and Alter Function
      • Discovering Enzyme Activators
      • Analyzing Mechanisms of Drug Resistance via Chemical Biology
      • Analyzing Enzyme Conformational Dynamics, Substrate Binding, and Catalysis
      • Effective Drug Targeting of Pathogens via Medicinal Chemistry
    • Computational Chemistry and Biology
      • Computational Chemistry and Biology Overview
      • Modeling protein regulation via allostery and post-translational modifications
      • Visualizing and integrating bioinformatics and biomolecular data
      • Modeling membrane permeation to optimize pharmacokinetics
      • Determining enzyme function by predicting substrate specificity
    • Physical Biology
      • Physical Biology Overview
      • Proteomics, post-translational modifications, and epigenetics
      • Capturing conformational dynamics and transient interactions
      • Viewing the cell’s inner life via light microscopy
    • Protein and Cellular Engineering
      • Protein and Cellular Engineering Overview
      • Monitoring enzyme activity and disease biomarkers
      • Generating human proteome antibodies via phage display and directed evolution
      • Globally analyzing and dissecting apoptosis
      • Proximity tagging of protein-protein interactions
      • Investigating cellular interactions in tissues
      • Creating fluorescent probes targeting the genome and key bio-pathways
      • De novo design of catalytic and membrane proteins
      • Probing and modulating membrane proteins
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Media Coverage

Bay Area must enable economic, equitable recovery

SF Chronicle
Tue May 26, 2020

UCSF team has discovered drugs that block coronavirus, paving way for ‘a better drug sooner’

SF Chronicle
Thu Apr 30, 2020

Explore molecular targets in daring new ways

UCSF
Tue Jun 12, 2018

Protein Engineering May Be the Future of Science

Bloomberg
Tue Mar 27, 2018

The search for the perfect painkiller

The Guardian
Sun Jan 28, 2018

Stem Cells Made by Modifying the Epigenome with CRISPR

The Scientist
Thu Jan 25, 2018

Tissue Engineers Hack Life’s Code for 3-D Folded Shapes

Quanta Magazine
Thu Jan 25, 2018
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Media coverage archive

  • 2023 (1)
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  • 2016 (22)
  • 2015 (19)
  • 2014 (3)
  • 2009 (1)
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Science is the foun­da­tion of the School of Pharmacy’s pi­o­neer­ing re­search, in­di­vid­ua­lized pa­tient care, and un­par­al­leled PharmD and PhD ed­u­ca­tion pro­grams.
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