The opportunities in Pharmaceutical Chemistry for high impact discovery and design for human betterment have never been greater. The pioneers of this department were rooted in physical, computational, analytical, synthetic and enzyme chemistry. This faculty helped to forge modern approaches for structure-based drug and protein design, mass spectrometry, NMR spectroscopy and computer-aided visualization of macromolecules. The group has flourished from this base and currently represents world-class leaders in drug and protein design, de novo protein structure prediction, proteomics, and synthetic and chemical biology. We seek to innovate computational, chemical, and biochemical approaches to deepen our understanding of the principles of molecular recognition and cell circuit design. Our dream is for systematic and predictive algorithms to discover safe and effective pharmaceuticals, and for the construction of synthetic biosystems to understand and improve the human condition.
September 16, 2013: Bo Huang is published in the Proceedings of the National Academy of Sciences (PNAS): Counting molecules in single organelles with superresolution microscopy allows tracking of the endosome maturation trajectory.
September 3, 2013: Matt Jacobson and John Gross are published in Structure: Active site conformational dynamics are coupled to catalysis in the mRNA decapping enzyme Dcp2.
We welcome our newest faculty member Jason Gestwicki, PhD! Chemical biologist Jason Gestwicki, PhD joins the department of Pharmaceutical Chemistry as an associate professor-in-residence. This is a joint hire made with the Institute of Neurodegenerative Diseases (IND). Dr. Gestwicki is a leader in the area of drug discovery for tauopathies and polyglutamine disorders.
John Gross is a keynote speaker at the 20th Annual West Coast Retrovirus Meeting to be held in Palm Springs, California.
T32 training grants for the Biophysics program and the Bioinformatics program were both successfully renewed.
Congratulations to these recent fellowship winners:
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