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Department of Pharmaceutical Chemistry
UCSF School of Pharmacy
Pharmaceutical Chemistry

Introduction

The opportunities in Pharmaceutical Chemistry for high impact discovery and design for human betterment have never been greater. The pioneers of this department were rooted in physical, computational, analytical, synthetic and enzyme chemistry. This faculty helped to forge modern approaches for structure-based drug and protein design, mass spectrometry, NMR spectroscopy and computer-aided visualization of macromolecules. The group has flourished from this base and currently represents world-class leaders in drug and protein design, de novo protein structure prediction, proteomics, and synthetic and chemical biology. We seek to innovate computational, chemical, and biochemical approaches to deepen our understanding of the principles of molecular recognition and cell circuit design. Our dream is for systematic and predictive algorithms to discover safe and effective pharmaceuticals, and for the construction of synthetic biosystems to understand and improve the human condition.

News

December 3, 2013: Brad Gibson was published in Cell Metabolism for SIRT5 Regulates the Mitochondrial Lysine Succinylome and Metabolic Networks.

December 2013: Michelle Arkin was a finalist for the SLAS Innovation Award.

November 20, 2013: Anthony O’Donaghue is a member of the Craik Lab and won the 2013 Bioanalysis Young Investigator Award. Press release: Announcing the Winner of the Bioanalysis Young Investigator 2013 Award.

October 15 & 21, 2013: Adam Renslo had a pair of papers appear in PNAS:

October 13, 2013: Zev Gartner is published in the journal Nature Methods (Farlow et al): Formation of targeted monovalent quantum dots by steric exclusion. Also see Zev Gartner receives NIH New Innovator Award to build complex human breast tissue.

September 2013: Al Burlingame renewed the APNRR Proteomics Platform project grant with the Dr. Miriam and Sheldon G. Adelson Medical Research Foundation.

More School news: News Archive