Categories: Research

Scientists at the Gladstone Institutes, the Diabetes Center at UCSF, and the UCSF School of Pharmacy have converted human skin cells into fully functional pancreatic cells that produce insulin in response to changes in glucose levels. Transplanted into mice, the cells protected the animals from...

How do you discover new drugs against diseases such as cancer?

Cataracts are the leading cause of blindness worldwide, the leading cause of vision loss in the United States, and cases are increasing with an aging population. Currently the condition can be treated with surgery—an expensive intervention that leaves most patients blinded in developing countries...

More than a quarter of all drugs work by targeting one of a large family of proteins called G-protein-coupled receptors (GPCRs). Hundreds of different GPCRs are embedded in cell membranes, converting stimuli from the outside world—neurotransmitters, hormones, even light—into intracellular signals...